Сюжеты для игр часто берутся из известных произведений литературы или кинофильмов, причем пользуются популярностью как фэнтезийные сюжеты, так и научно-фантастические.

Список игровых миров:

Agone (Fantasy setting)
Al-Qadim (D&D Arabian setting, situated on Abeir-Toril)
Aldea (the world of Blue Rose)
Arcanis (D&D, set in the continent of Onara on the world of Arcanis)
Arcana Unearthed
Aventuria (The setting of The Dark Eye)
Banestorm (GURPS)
Battleaxe RPG (set in the World of Mordredica)
Birthright (D&D, situated on Aebrynis)
Blackmoor (D&D)
Caliphate Nights (a True20 setting)
Castlemourn
Council of Wyrms (AD&D, in which PCs play Dragons)
Dark Sun (D&D, situated on Athas)
Dragonlance (D&D, situated on Krynn)
DragonMech (A D&D steampunk-fantasy setting with mecha)
Diablo universe (set on the World of Sanctuary)
Earthdawn (situated on Barsaive)
Eberron (D&D setting that blends fantasy & technology)
Empire of the Petal Throne (situated on Tekumel)
EverQuest (situated on Norrath)
Exodus (D&D set on the world of Exodus)
Forgotten Realms (D&D, situated on Abeir-Toril)
Forcelia (D&D (not TSR's official), Record of Lodoss War, Sword World RPG, Legend of Crystania and Rune Soldier)
Gaea (the setting of Tales of Gaea)
Glorantha
Greyhawk (D&D, situated on Oerth)
Grimm
Hârn (situated on Kethira)
Hyborian Age is the setting of Robert E. Howard's Conan, and, naturally, is the base for the following RPG adaptations: old TSR Conan RPG, GURPS Conan and Conan d20.
Iron Kingdoms is a setting created by Privateer Press where technology and magic are complementary forces, which lends it a unique character also demonstrated by the Warmachine tabletop wargame set in the same world.
Kara-Tur (D&D Oriental setting, situated on Abeir-Toril created for the 1st edition of 'Oriental Adventures' but not used for the 3rd edition product of the same name)
Kingdoms of Kalamar (D&D, situated on Tellene)
Known Realms (D&D setting, born out of the Dungeon Crawl Classics adventures, and situated in the world of Áereth)
Ksaren (Third Dawn)
Layonara
Magnamund (the world the Lone Wolf d20 rpg takes place in)
Mundana (from the Swedish role-playing game Eon [1])
Middle-earth (The Lord of the Rings Roleplaying Game)
Midgard
Midgard (Alshard)
Midnight (D20)
Mystara (D&D)
New Europa is the name of the European continent in Castle Falkenstein.
Oathbound (D20)
Planescape (D&D alternative dimension setting, which also allows crossover campaigns using multiple campaign settings)
Ptolus
Rokugan (of the Legend of the Five Rings used for the 3rd edition of the D&D 'Oriental Adventures')
Scarred Lands (d20 setting, situated on Scarn) by Sword & Sorcery Studios (part of White Wolf)
Shadow World (situated on Kulthea) (Rolemaster) by Iron Crown Enterprises
Spelljammer (D&D fantasy-space setting, which also allows crossover campaigns using multiple campaign settings)
Tékumel (The setting of Empire of the Petal Throne)
The Kyngdoms (A very large, very detailed and complete d20 setting with a full color map, in depth national identities, interesting history, plus tons of information. Books are available on rpgnow.com)
Tormenta (D20 and 3D&T, situated on Arton; a campaign setting created in Brazil originally for GURPS, AD&D, Trevas)
Thunder Rift (D&D)
Urban Arcana Earth (for d20 Modern)
Uresia (BESM2 and d20)
Warcraft (d20)
Warhammer Fantasy Roleplay (situated on The Old World)
Westeros (A Game of Thrones)
Wheel of Time (d20)